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Updated: Jul 6, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

细胞质体成分TRIM5alpha限制了老世界子的HIV-1感染

Matthew Stremlau1, Christopher M Owens, Michel J Perron

  • 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|February 27, 2004
PubMed
概括

宿主细胞因子限制人类免疫缺陷病毒1型 (HIV-1) 在灵长类动物中的复制. TRIM5alpha蛋白阻止HIV-1进入子细胞,解释了特定物种的病毒分布和天生的抵抗力.

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