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Updated: May 13, 2026

Isolating Nasal Olfactory Stem Cells from Rodents or Humans
09:19

Isolating Nasal Olfactory Stem Cells from Rodents or Humans

Published on: August 22, 2011

从嗅觉感官神经元克隆的小鼠

Kevin Eggan1, Kristin Baldwin, Michael Tackett

  • 1Whitehead Institute for Biomedical Research and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|March 3, 2004
PubMed
概括

科学家们用成熟的嗅觉感官神经元的细胞核克隆小鼠. 这表明终端分化的神经元可以被重新编程以进行成功的克隆,这是发育生物学上的重大进展.

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Perforated Patch-clamp Recording of Mouse Olfactory Sensory Neurons in Intact Neuroepithelium: Functional Analysis of Neurons Expressing an Identified Odorant Receptor

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Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...