在患有心力衰竭和左束分支阻塞的患者中,左心室激活的特征
Angelo Auricchio1, Cecilia Fantoni, Francois Regoli
1Division of Cardiology, University Hospital, Leipzigerstrasse 44, D-39120 Magdeburg, Germany. angelo.auricchio@medizin.uni-magdeburg.de
Circulation
|March 3, 2004
概括
左心室 (LV) 中的U形激活模式是由左束枝阻塞 (LBBB) 患者的功能性阻塞线引起的. 非接触式绘图有助于确定心脏再同步治疗的最佳部位.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗成像医学成像
背景情况:
- 在扩张左心室 (LV) 与左束分支区块 (LBBB) 中进行常规激活映射,由于记录地点的可用性和精度而受到限制.
- 准确的LV激活映射对于理解心力衰竭病理生理学和指导治疗至关重要.
研究的目的:
- 为了研究心力衰竭和LBBB形态的患者的LV激活序列.
- 评估同时使用3D接触和非接触映射在表征LV激活模式中的实用性.
- 确定功能阻断线对LV激活的影响及其在心脏再同步治疗中的潜在作用.
主要方法:
- 在24名心力衰竭和LBBB.患者中,同时进行了3D接触和非接触测绘.
- 在内在节奏和异步节奏期间研究了LV激活序列.
- 分析了导电块线路的位置和功能行为.
主要成果:
- 在大多数患者中观察到"U形"激活波面,这是由于跨壁线的阻断.
- 阻塞线位于前面,侧面或下面,影响QRS和激活持续时间.
- 在异步步进过程中,在区块线位置的功能变化得到了证明.
结论:
- 一个U形导电模式是由LV中的一个功能线块强加的,延长了激活时间.
- 无接触映射有效评估功能阻断,有助于确定心脏重同步治疗的最佳标.
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