通过13C交叉极化魔法角旋转核磁共振光谱学确定膜运输蛋白的基质亲和力

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Updated: Jul 20, 2026

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins
13:59

Methods to Identify the NMR Resonances of the 13C-Dimethyl N-terminal Amine on Reductively Methylated Proteins

Published on: December 12, 2013

Simon G Patching1, Adrian R Brough, Richard B Herbert

  • 1Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Sackville Street, Post Office Box 88, Manchester M60 1QD, United Kingdom.

Journal of the American Chemical Society
|March 12, 2004
PubMed
概括

新的固态NMR方法精确地测量了基质与NupC和GusB等膜运输蛋白的结合. 这些技术量化了结合亲缘关系,有助于各种膜蛋白的药物和抗生素开发.

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