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A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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候选原型瘤基因bcl-3编码了一种转录因子NF-kappa B的子单元特异性抑制剂

F G Wulczyn1, M Naumann, C Scheidereit

  • 1Otto Warburg Laboratorium, Max Planck Institut für Molekulare Genetik, Berlin, Germany.

Nature
|August 13, 1992
PubMed
概括

原型瘤基因bcl-3编码一种蛋白质,该蛋白质作为NF-kappa B p50亚单元的特定抑制剂. 这一发现揭示了NF-kappa B转录因子参与细胞生长和疾病的新调节机制.

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