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Updated: Mar 2, 2026

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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通过对自然代谢物敏感的 ribozyme 控制基因表达

Wade C Winkler1, Ali Nahvi, Adam Roth

  • 1Department of Molecular, Cellular and Developmental Biology, Yale University, PO Box 208103, New Haven, Connecticut 06520-8103, USA.

Nature
|March 19, 2004
PubMed
概括

科学家们发现了一种新的 ribozyme,通过感知代谢物水平来控制细菌中的基因表达. 这一发现表明,古代基于RNA的遗传开关可能仍然在现代细胞中起作用.

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