通过β-catenin/MAPK复合物的酸化促进了C. elegans信号响应细胞中14-3-3介导的TCF/POP-1的核出口

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Updated: Jul 13, 2026

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract
09:41

Reconstitution Of β-catenin Degradation In Xenopus Egg Extract

Published on: June 17, 2014

Miao-Chia Lo1, Frédérique Gay, Raanan Odom

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA.

Cell
|April 7, 2004
PubMed
概括

通过促进其酸化和核出口,Wnt/MAPK信号降低了C. elegans胚胎中的POP-1水平. 这一过程涉及β-catenin WRM-1 和 MAP 激酶 LIT-1,确保了适当的细胞命运.

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