在心肺复苏期间,高通风引起的低血压
Tom P Aufderheide1, Gardar Sigurdsson, Ronald G Pirrallo
1Department of Emergency Medicine, Medical College of Wisconsin, Milwaukee, USA.
Circulation
|April 7, 2004
概括
在心肺复苏 (CPR) 期间过度通风是常见的. 动物研究表明,高通风显著降低冠状动脉 perfusion 压力和生存率,突出了改善心肺复苏技术的关键需求.
科学领域:
- 紧急医疗 紧急医疗
- 心肺生理学 心肺生理学
- 复苏科学复苏科学 复苏科学
背景情况:
- 观察性研究表明,在非医院心肺复苏 (CPR) 期间,救援人员经常高呼吸.
- 过度通风可能会在复苏过程中对患者的结果产生负面影响.
研究的目的:
- 量化人类心肺复苏中过度通风的程度.
- 为了确定动物模型中的过度通风率是否会降低冠状动脉 perfusion 压力和心肺复苏期间的生存率.
主要方法:
- 在接受心肺复苏的13名成年患者中,通风速率和持续时间被电子记录.
- 血动力学参数和生存率在接受心肺复苏的猪中进行了评估,其通风速 (12,20,30次/分钟) 和气体混合率各不相同.
主要成果:
- 人类心肺复苏显示平均通风率为30次/分钟,没有幸存者.
- 在猪中,增加的通风率 (30比12次呼吸/分钟) 显著提高胸内压力 (17.5比7.1毫米升/分钟) 和降低冠状动脉 perfusion 压力 (16.9比23.4毫米升).
- 猪的生存率显著低于30次呼吸/分钟 (1/7) 与12次呼吸/分钟 (6/7) 相比.
结论:
- 专业的救援人员经常在医院外的心肺复苏过程中高呼吸患者.
- 在动物模型中,在心肺复苏过程中过度通风会导致有害的血液动力学变化和降低生存率.
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