绝经后雌激素用于治疗热:临床应用
1Oregon Evidence-based Practice Center, Department of Medical Informatics and Clinical Epidemiology, and Oregon Health and Science University, Portland 97239, USA. nelsonh@ohsu.edu
JAMA
|April 8, 2004
概括
由于新的指导方针,绝经后雌激素的使用发生了转变. 本文检查了当前的证据,以启动或停止激素治疗的妇女经历热或长期使用.
科学领域:
- 生殖医学 生殖医学
- 内分泌学 在内分泌学.
- 妇女健康 妇女健康
背景情况:
- 自2002年妇女健康倡议发现以来,绝经后雌激素治疗的使用有了显著的发展.
- 目前主要卫生组织的建议建议不要使用雌激素和孕激素/孕来预防慢性疾病.
研究的目的:
- 将绝经后雌激素使用的最新证据应用于临床决策.
- 针对两个具体的情景:开始治疗绝经前期热和停止长期使用者的治疗.
主要方法:
- 关于绝经后激素治疗的当前证据的审查和综合.
- 在临床管理场景中应用基于证据的指导方针.
主要成果:
- 更新的建议影响了激素治疗开始和延续的方法.
- 证据支持基于症状严重程度和风险因素的个性化治疗决定.
结论:
- 绝经后雌激素治疗的临床管理需要遵守当前的证据和指导方针.
- 需要仔细考虑,无论是开始治疗以缓解症状还是停止长期使用.
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