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胰岛素瘤和胰岛素拼接变体的表达

Alexandra H Minn1, Mark Kayton, Dominique Lorang

  • 1Department of Medicine, Endocrinology Section, University of Wisconsin-Madison, Madison, WI 53792, USA.

Lancet (London, England)
|April 9, 2004
PubMed
概括

在胰岛素瘤中发现的一种新型胰岛素拼接变体,显著增加了胰岛素的产生. 这一发现有助于解释这些瘤是如何导致高胰岛素血症的一个关键疾病特征.

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Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...