晚发性作为随后中风的预测因素
Paul Cleary1, Simon Shorvon, Raymond Tallis
1Brownlee Centre, Gartnavel General Hospital, Glasgow, UK.
Lancet (London, England)
|April 15, 2004
概括
晚年发作显著增加了中风风险. 这项研究发现,60岁以后经历新发作的人面临后续中风风险近三倍的风险.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 老年病的医生 老年病的医生
背景情况:
- 脑血管疾病是已知的晚年的原因之一.
- 在老年人中,新发作和随后的中风风险之间的关系尚未完全理解.
研究的目的:
- 调查假设,在60岁以上没有中风史的人群中,新发作与未来中风的风险增加有关.
主要方法:
- 英国通用实践研究数据库的研究包括4709名新发作发作的人 (年龄≥60岁) 和4709名匹配对照.
- 排除标准包括先前的脑血管疾病,脑损伤,瘤,物质滥用或痴呆症.
- 分析了患者记录,以确定随后的中风诊断.
主要成果:
- 逻辑等级测试显示,两组之间无中风存活率存在非常显著的差异 (p<0.0001).
- 考克斯模型估计,与对照组相比,发作组中风的相对风险为2.89 (95% CI 2.45-3.41).
结论:
- 生命晚期发作与中风风险的大幅增加有关.
- 需要进一步的研究来评估旨在预防晚年发作患者中风的干预措施.
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