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拉巴罗镜切除直腰肌癌:前性随机试验

Ka Lau Leung¹, Samuel P Y Kwok, Steve C W Lam

¹Department of Surgery, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong. leungkl@msn.com

Lancet (London, England)

|April 15, 2004

概括

乳房镜切除直肠西格癌的结果显示,与开放性手术相比,存活率和疾病控制率相当. 虽然恢复更好,但使用腹腔镜的决定取决于评估改善的短期结果.

科学领域:

手术瘤学手术瘤学
胃肠道手术胃肠道手术
最少侵入性的手术

背景情况:

laparoscopic结肠直肠癌切除可以改善恢复,但长期的瘤结果需要评估.
脊柱状肌肉癌的治疗需要在手术方法和患者存活率之间保持平衡.

研究的目的:

为了比较腹腔镜切除和直腰肌癌的开放切除之间的长期生存和疾病控制.
在这个患者队列中评估腹腔镜手术的瘤安全性.

主要方法:

这是一项随机对照试验,涉及403名直肠西格瘤癌患者.
腹腔镜辅助切除与传统开放切除的比较.
评估存活率和无病间隔作为主要终点,以及术后数据和成本分析.

主要成果:

腹腔镜切除的五年生存率为76.1%,开放切除的72.9%.
五年无病率为75.3%的腹腔镜和78.3%的开放切除.
腹腔镜手术的手术时间较长,但术后恢复更好,瘤边缘,淋巴结检索,发病率和死亡率相似.

结论:

乳房镜切除直肠西格瘤癌是瘤安全的,不影响生存或疾病控制.
腹腔镜技术的采用应考虑增强短期恢复和潜在成本影响之间的权衡.

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