为便失禁而进行神经脊柱神经刺激:多中心研究
Klaus E Matzel1, Michael A Kamm, Michael Stösser
1Department of General Surgery, University Hospital Erlangen, Erlangen, Germany. Klaus.Matzel@chir.imed.uni-erlangen.de
Lancet (London, England)
|April 20, 2004
概括
圣神经刺激显著改善了便失禁,通过减少发作,提高了关问题患者的生活质量. 当其他方法失败时,这种治疗提供了一个可行的选择.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 神经调节是一种神经调节.
- 盆地底疾病 盆地底疾病
背景情况:
- 在有功能缺陷但形态完整的关节的患者中,便失禁的治疗选择有限.
- 保守的治疗方法往往失败,需要替代治疗方法.
研究的目的:
- 调查神经神经刺激 (SNS) 在改善禁欲和生活质量的有效性.
- 评估SNS作为特定患者群体便失禁的治疗方法.
主要方法:
- 一个多中心前性试验,涉及37名便失禁患者.
- 34名患者在测试刺激期后接受了神经刺激器植入.
- 通过日常日记评估禁欲;使用ASCRS和SF-36问卷测量生活质量.
主要成果:
- 显著减少每周无 incontinence 事件 (平均16.4至2.0) 和无 incontinence 的天数.
- 减少对染色和使用的需求.
- 改善了推迟排便的能力,并在多个尺度上提高了生活质量.
结论:
- 圣神经刺激为便失禁的患者提供了显著的节制改善.
- SNS提高了生活质量,为精心挑选的患者提供了有价值的治疗选择.
- 这种神经调节技术解决了难治性便失禁管理的关键未满足需求.
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