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Updated: May 5, 2026

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
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B7-1/B7-2共刺激调节了低密度脂蛋白受体缺乏小鼠的斑块抗原特异性T细胞反应和动脉生成

Chiara Buono1, Hong Pang, Yasushi Uchida

  • 1Immunology Research Division and the Vascular Research Division, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass 02115, USA.

Circulation
|April 21, 2004
PubMed
概括

B7-1/B7-2共刺激途径对于驱动动动脉硬化的T细胞反应至关重要. 阻止这种途径会减少小鼠的病变发展和T细胞炎症活性.

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