用重复皮肤干预治疗的sirolimus-eluting后支架缩:晚期血管学和临床结果
Pedro A Lemos1, Carlos A G van Mieghem, Chourmouzios A Arampatzis
1Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands.
Circulation
|May 19, 2004
概括
在用重复的皮肤穿干预 (SES) 插入西罗林木斯排泄支架后治疗缩症显示出低于最佳的结果. 复发性复缩率很高,特别是在气球扩张时,这表明需要改进策略.
科学领域:
- 心血管干预 心血管干预
- 干预心脏病学 干预心脏病学
- 医疗器械研究 医疗器械研究
背景情况:
- 植入西罗利斯排泄支架 (SES) 后的复原症是一个临床挑战.
- 评估对SES后静脉缩重复皮肤干预的结果对于患者管理至关重要.
研究的目的:
- 评估SES安置后重复皮肤干预以检测SES复原症的患者的临床和血管学结果.
- 为了确定影响SES后复发缩治疗后复发缩的因素.
主要方法:
- 对24名患者 (27个病变) 的回顾性分析,这些患者因后SES复原而接受治疗.
- 干预措施包括气球血管整形,裸体金属支架和重复药物排泄支架植入 (SES和帕克利塔塞尔排泄支架).
- 平均随访时间为279天,以评估无事件生存率和复发性复原率.
主要成果:
- 大多数的复 (93%) 是静脉静脉.
- 重复的药物释放支架植入是最常见的再干预 (85%).
- 总体复发复原率为42.9%;无事件生存率为70.8%. 高胆固醇血症,早期治疗需求和气球血管造形术与更高的复发风险有关.
结论:
- 通过重复的皮肤间干预,特别是气球扩张来治疗后SES缩,仍然是不理想的.
- 虽然对新发性病变的重复药物释放支架植入显示出更好的结果 (18.2%的复发率),但整体策略需要进一步调查和改进.
- 需要进行进一步的研究,以优化治疗方法,在西洛利木斯释放支架植入后管理复原症.
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