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在MFG-E8缺乏的小鼠中,自身免疫性疾病和亡细胞的吸收受损

Rikinari Hanayama1, Masato Tanaka, Kay Miyasaka

  • 1Department of Genetics, Osaka University Medical School, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.

Science (New York, N.Y.)
|May 25, 2004
PubMed
概括

乳脂球体表皮生长因子8 (MFG-E8) 对于巨细胞来说至关重要,以清除亡性B细胞. 在小鼠中,MFG-E8 缺乏导致清除功能受损,导致大和自身免疫性淋巴结核炎.

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