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Updated: Jul 22, 2026

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers
10:08

Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers

Published on: July 25, 2012

蛋白质折叠的早期步骤的实验解决:测试分子动力学模拟

Dung M Vu1, Eric S Peterson, R Brian Dyer

  • 1Bioscience Division, MS J586, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA.

Journal of the American Chemical Society
|May 27, 2004
PubMed
概括

时间解析的Tyr光和红外光谱学揭示了蛋白质折叠的动态. 没有观察到螺旋1形成的快速过程,这表明它发生在螺旋束组装的微秒阶段.

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相关概念视频

Mechanical Protein Functions01:58

Mechanical Protein Functions

Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.