在1.5T时使用质子NMR成像评估回后心肌出血
C S Lotan1, A Bouchard, G B Cranney
1Department of Medicine, University of Alabama, Birmingham 35294.
Circulation
|September 1, 1992
概括
核磁共振 (NMR) 成像可以检测和量化急性心肌梗塞中转血后的心脏内出血. 这种非侵入性技术有助于描述心脏病发作病理学,并评估出血的作用.
科学领域:
- 心血管成像 - 心血管成像
- 生物医学工程 生物医学工程
- 病理学 病理学 病理学
背景情况:
- 在急性心肌梗塞再注射后,心内出血很常见.
- 由于检测方法有限,它的意义尚不清楚.
- 核磁共振 (NMR) 成像的检测潜力被评估.
研究的目的:
- 评估核磁共振 (NMR) 成像用于检测和量化心内出血后的输血.
- 建立一种非侵入性方法来评估心肌梗塞中出血.
主要方法:
- 在切除的狗心脏上进行了ex vivo旋回回声NMR成像 (1.5-T).
- 冠状动脉封闭,然后再输血.
- 与组织学和放射标记的微球/红细胞进行对出血评估的比较.
主要成果:
- 在14/16个重灌心脏中,NMR检测到心肌内出血.
- 在NMR上降低信号强度 (SI) 区域与宏观出血相关.
- 通过NMR进行的出血大小与组织学 (r=0.96) 和51Cr标记 (r=0.78) 方法相关性很好.
- 在出血区 (58±9毫秒) 和非出血心脏病发作区 (98±13毫秒) 中,T2放松时间显著缩短.
结论:
- 核磁共振成像为检测和量化心内出血提供了一种非侵入性方法.
- 这种技术可以帮助鉴定急性心肌梗塞病理.
- 核磁共振可能有助于评估出血在再注射治疗结果中的作用.
相关概念视频
01:24Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
01:21Imaging Studies for Cardiovascular System IV: CMRI
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...