在因大动脉狭窄而进行大动脉置换的患者中,左心室内腔内流量的异常加速. 这是一种高术后发病率和死亡率的标志物
G Aurigemma1, S Battista, D Orsinelli
1Noninvasive Laboratory, University of Massachusetts Medical Center, Worcester 01655.
Circulation
|September 1, 1992
概括
由于大动脉狭窄而进行大动脉置换后,异常的内腔内流加速表明风险更高. 这一通过多普勒心声学识别的发现与患者死亡率和发病率的增加有关.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏外科手术 心脏外科手术
背景情况:
- 大动脉狭窄是一种常见的膜性心脏病.
- 大动脉置换 (AVR) 是严重的大动脉狭窄症的标准治疗方法.
- 对AVR结果的术后评估至关重要.
研究的目的:
- 调查AVR后异常内腔内流加速的患者的临床和心声学特征.
- 确定这一发现与术后结果的关联.
主要方法:
- 对53名因大动脉狭窄而接受AVR的患者进行了回顾性审查.
- 手术后的多普勒回声心脏图,以评估内腔内流量.
- 对有异常流量加速和没有异常流量加速的患者进行比较.
主要成果:
- 13名患者 (1组) 显示出异常的内腔内流加速 (平均梯度为104.6mmHg).
- 第1组有明显的腹腔几何结构 (过度缩,较小的腔,较高的射出分数).
- 第1组经历了较高的术后死亡率 (38%对12%) 和发病率.
结论:
- 在AVR后异常的内腔内流加速与特定的心室几何和超正常的功能有关.
- 这一发现是术后发病率和死亡率增加的标志物.
- 多普勒心电回声学有助于风险分层和治疗指导.
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