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相关概念视频

Olfaction01:25

Olfaction

The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
Taste Buds and Receptors01:20

Taste Buds and Receptors

Gustation, or the sense of taste, is intrinsically linked to the anatomical structures located on the tongue. This organ's surface, along with the entirety of the oral cavity, is adorned with stratified squamous epithelium. Evident on the tongue are elevated structures known as papillae (singular = papilla), which house the mechanisms for the transduction of gustatory stimuli. Four distinct types of papillae exist, each identified by their unique morphological attributes: the circumvallate,...
Respiratory System Abnormal Finding II: Palpation and Auscultation01:31

Respiratory System Abnormal Finding II: Palpation and Auscultation

In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Auditory Perception01:17

Auditory Perception

The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex. This...

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相关实验视频

Updated: Jul 11, 2026

A Wind Tunnel for Odor Mediated Insect Behavioural Assays
05:25

A Wind Tunnel for Odor Mediated Insect Behavioural Assays

Published on: November 30, 2018

周边嗅觉突出的产后细化 周边嗅觉突出的产后细化

Dong-Jing Zou1, Paul Feinstein, Aimée L Rivers

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA. dz98@columbia.edu

Science (New York, N.Y.)
|June 5, 2004
PubMed
概括

嗅球中的淋巴细胞成熟取决于特定发育时期的感官输入. 通常是短暂的早期异质块,当感官输入被阻止时会持续存在,这表明神经元存活时间长.

科学领域:

  • 神经科学是一个神经科学.
  • 嗅觉系统的开发和开发
  • 感官处理 感官处理

背景情况:

  • 从嗅觉上皮层到嗅觉球泡的轴突突出,形成称为球粒的结构.
  • 淋巴体组织是基于由嗅觉感官神经元表达的特定气味受体.
  • 这些球粒的成熟过程是复杂的,并未完全理解.

研究的目的:

  • 为了研究不同气味受体的球成熟的时间动态.
  • 确定感官输入和敏感时期在球发育中的作用.
  • 检查在感官剥夺条件下异质质结构的持久性.

主要方法:

  • 利用基因向小鼠研究嗅觉系统发育.
  • 通过单边的鼻孔关闭来操纵感官输入,以诱导感官剥夺.
  • 在不同的发育阶段和实验条件下分析了球组织和神经元存活率.

主要成果:

  • 对于不同的,但相似的气味受体,淋巴细胞成熟表现出不同的时间过程.
  • 在特定的敏感时期,感官输入对于适当的球成熟至关重要.
  • 不同类型的球体,即表达不同受体的神经元的轴突聚集的地方,通常会随着年龄的增长而消失.
  • 单侧鼻膜的关闭导致这些异质块在成年小鼠中持续存在.

更多相关视频

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period
07:13

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period

Published on: March 1, 2024

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

相关实验视频

Last Updated: Jul 11, 2026

A Wind Tunnel for Odor Mediated Insect Behavioural Assays
05:25

A Wind Tunnel for Odor Mediated Insect Behavioural Assays

Published on: November 30, 2018

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period
07:13

Experience-Dependent Remodeling of Juvenile Brain Olfactory Sensory Neuron Synaptic Connectivity in an Early-Life Critical Period

Published on: March 1, 2024

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice
09:30

Precision Induction and Distinction of Coughing and Sneezing Reflexes in Mice

Published on: October 3, 2025

  • 嗅觉感官神经元的长期存活可能有助于异质质细胞的持久性.
  • 结论:

    • 嗅觉球膜发育是一个动态的过程,受感官输入时间的影响.
    • 在发育过程中,存在特定的敏感时期,用于正确组织嗅觉灯泡电路.
    • 感官体验在消除异常的轴突连接和完善球结构方面发挥着至关重要的作用.
    • 在感官剥夺下异质质细胞的持久性突出显示了正常电路的精细化依赖于感官体验,并表明神经元生存机制的作用.