撒哈拉以南非洲的结核病和艾滋病毒感染
K M De Cock1, B Soro, I M Coulibaly
1Projet RETRO-CI, Abidjan, Ivory Coast.
JAMA
|September 23, 1992
概括
人类免疫缺陷病毒 (HIV) 严重影响撒哈拉以南非洲的结核病,增加死亡率. 解决这个被忽视的健康问题需要大量的资源用于诊断和护理.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 撒哈拉以南非洲面临着人类免疫缺陷病毒 (HIV) 和结核病 (TB) 的双重负担.
- 艾滋病毒和结核病之间的相互作用在该地区带来了独特的临床和病理挑战.
- 了解公共卫生影响对于有效的干预策略至关重要.
研究的目的:
- 审查非洲撒哈拉以南地区艾滋病毒相关结核病的流行病学,临床和病理学特征.
- 检查这种共同流行病对公共卫生的影响.
- 综合该地区关于艾滋病毒-结核病的当前知识.
主要方法:
- 系统审查已发表的医学文献 (英语和法语) 和会议记录.
- 精选了与非洲和全球HIV感染和结核病最相关的文章.
- 直接报告从精选文献中获得的定量数据 (例如,艾滋病毒血清流行率) 和定性发现.
主要成果:
- 在撒哈拉以南非洲的结核病患者中报告的高艾滋病毒感染率 (20-67%).
- 结核病病例的同时增加与艾滋病的出现在几个非洲国家.
- 结核病被确定为艾滋病患者在科特迪瓦阿比让最常见的机会性感染,艾滋病毒阳性个体的死亡率明显较高.
结论:
- 艾滋病毒疫情深刻改变了撒哈拉以南非洲的结核病流行病学.
- 与艾滋病毒相关的结核病是一个被忽视的全球卫生问题,需要大量的资源投资.
- 加强人力和物力资源对于应对这种共同流行病至关重要.
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