在导管切除过程中心房动周期长度和诱导性的变化及其与结果的关系
Michel Haïssaguerre1, Prashanthan Sanders, Mélèze Hocini
1Hôpital Cardiologique du Haut-Lévêque, Avenue de Magellan, 33604 Bordeaux, France. jacques.clementy@pu.u-bordeaux2.fr
Circulation
|June 9, 2004
概括
心房移除延长了心房的周期长度,减少了AF频率. 在切除过程中终止AF和预防诱导性预测了成功的结果.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 导管切除对人类心房周期长度 (AFCL) 的影响仍未评估.
- 心房动 (AF) 是一种常见的心律失常症,需要有效的治疗策略.
研究的目的:
- 在AF患者的导管切除过程中评估AFCL的修饰.
- 评估肺静脉 (PV) 隔离和 mitra 静脉移对 AFCL 和诱导性的影响.
主要方法:
- 长期AF的70名患者被随机分离到PV隔离或额外的 mitra isthmus 移除.
- 在切除手术之前和之后,在冠状动脉鼻测量了AFCL.
- 在切除前和切除后评估AF诱导性,以确定手术成功.
主要成果:
- 在75%的患者中,PV隔离终止了AF,并观察到显著的AFCL延长.
- 线性切除也延长了AFCL,特别是在AF终止的患者中.
- 在57% (PV隔离) 和77% (线性切除) 的患者中,持续的AF在切除后是不可诱导的.
- 在7个月内,无心律失常的生存率为74% (PV隔离) 和83% (线性切除),与非诱导性相关.
结论:
- 对AF的导管切除导致AF频率下降.
- AFCL延长的程度与AF终止和诱导性预防有关.
- 在消去后预防AF诱导性是长期临床成功的强有力的预测指标.
相关概念视频
Magnetic Force On Current-Carrying Wires: Example
In a magnetic field, moving charges encounter a force. If a wire contains these moving charges, i.e., if the wire is carrying a current, then a force acts on the wire as well. Consider a pair of flexible leads holding a wire that is 40 cm long and 10 g in weight in a horizontal position. The wire is placed in a constant magnetic field of 0.40 T, as shown in Figure 1(a). Determine the magnitude and direction of the current flowing in the wire needed to remove the tension in the supporting leads.
Induction
An emf is induced when the magnetic field in a coil is changed by pushing a bar magnet into or out of the coil. emfs of opposite signs are produced by motion in opposite directions, and the directions of emfs are also reversed by reversing poles. The same results are produced if the coil is moved rather than the magnet—it is the relative motion that is important. The faster the motion, the greater the emf. Additionally, there is no emf when the magnet is stationary relative to the coil.
A...
A...
Lenz's Law
The direction in which the induced emf drives the current around a wire loop can be found through the negative sign. However, it is usually easier to determine this direction with Lenz's law, named in honor of its discoverer, Heinrich Lenz (1804–1865). Lenz's law states that the direction of the induced emf drives the current around a wire loop always to oppose the change in magnetic flux that causes the emf.
If a bar magnet is moved toward a coil such that the magnetic flux through the coil...
If a bar magnet is moved toward a coil such that the magnetic flux through the coil...


