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Updated: Jul 6, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
08:47

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation

Published on: March 5, 2018

通过caspase-1适配器ASC和Ipaf的炎症酶的差异激活

Sanjeev Mariathasan1, Kim Newton, Denise M Monack

  • 1Molecular Oncology Department, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.

Nature
|June 11, 2004
PubMed
概括

适配器ASC对于炎症酶激活和随后的IL-1β/IL-18成熟至关重要. Ipaf 特别介导细胞内病原体的 caspase-1 激活,影响炎症和细胞死亡途径.

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