在心房动的青少年中进行的电生理学发现,这些青少年心脏结构正常,心脏结构正常
Kumaraswamy Nanthakumar1, Yung R Lau, Vance J Plumb
1Division of Cardiovascular Diseases, University of Alabama at Birmingham, 1670 University Blvd, B140 Volker Hall, Birmingham AL 35294-0019, USA. kn@crml.uab.edu
Circulation
|June 16, 2004
概括
儿童的心房动 (AF) 通常是由肺静脉或左心房中的快速发射焦点引起的. 导管切除有效地消除了这些焦点,在大多数青少年患者中解决了AF.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 电子生理学 电子生理学
- 心脏节律失常症 心脏节律失常症
背景情况:
- 在儿科人群中,心房动 (AF) 是罕见的,其潜在机制尚不清楚.
- 了解儿童AF的电生理基础对于有效治疗至关重要.
研究的目的:
- 描述AF的儿科和青少年患者的电生理学发现.
- 评估导管切除在该人口群体中治疗AF的疗效.
主要方法:
- 侵袭性电生理学测试和心内测绘在9名青少年中进行,这些青少年有症状单独的AF.
- 导管切除向确定了自发性AF发病地点或快速发射的心房焦点.
- 一名患有复杂左心房焦点的患者接受了手术迷宫手术.
主要成果:
- 最常见的AF焦点来源是肺静脉 (n=5),左心房 (n=2) 和尖端 (n=3).
- 导管切除在88.9%的患者中取得了急性成功.
- 长期随访显示,77.8%的患者在没有药物的情况下保持心律不整;两名患者经历了AF复发,并用药物控制.
结论:
- 在心脏结构正常的青少年中,AF通常起源于肺静脉的焦点,左心房或crista terminalis.
- 这些焦点通常会触发不规则的心房动脉冲动.
- 这些焦点的导管切除是消除儿科和青少年患者复发性AF的有效策略.
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