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在大肠杆菌中以前体为导向的epothilone生物合成

Christopher N Boddy1, Kinya Hotta, Martha Lovato Tse

  • 1Departments of Chemical Engineering, Chemistry, and Biochemistry, Stanford University, Stanford, California 94305-5025, USA.

Journal of the American Chemical Society
|June 17, 2004
PubMed
概括

工程细菌现在可以使用前体导向生物合成方法生产抗癌药物epothilone C. 这种方法结合了化学合成和酶过程,以高效地生产药物.

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