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Bacterial Phylum Spirochaetes
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锡亚蛋白,HIF prolyl hydroxylases,以及对缺氧的生理反应

M Celeste Simon1

  • 1Howard Hughes Medical Institute, Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

Cell
|June 24, 2004
PubMed
概括

新的研究表明,Siah1a和Siah2 E3泛素连接酶向低氧诱导因子 (HIF) 基化酶进行降解. 这增加了细胞感知氧气水平和对缺氧反应的复杂性.

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