Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Binary Fission01:20

Binary Fission

67.7K
Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical.
67.7K
Cytoskeletal Proteins in Bacteria01:29

Cytoskeletal Proteins in Bacteria

4.5K
Bacterial cells were initially considered simple, randomly organized structures lacking a cytoskeleton. However, the discovery of cytoskeleton homologs in bacteria led to the change of this opinion. Bacterial cytoskeletal filaments regulate the cell shape, cell polarity, cell division, and partitioning of plasmids during cell division. It was later discovered that bacterial cytoskeletal proteins, mainly actin and tubulin homologs, are diverse compared to their eukaryotic counterparts. On the...
4.5K
Cohesins02:20

Cohesins

5.9K
Cohesin protein complexes are a molecular glue that holds two sister chromatids together. They play an important role both in mitosis and meiosis. In mitosis, all cohesin complexes present on the chromosomes are removed before the start of the anaphase stage.
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of...
5.9K
Nucleoid01:24

Nucleoid

1.9K
The nucleoid represents a structurally and functionally distinct region within prokaryotic cells, where the cell's DNA and associated proteins are housed. Unlike eukaryotic cells, prokaryotes lack a membrane-bound nucleus, and the nucleoid facilitates the organization and accessibility of the genetic material within this constraint. The DNA in most bacteria and archaea exists as a single, circular, double-stranded molecule that is highly compacted through supercoiling and interactions with...
1.9K
Binary Fission01:26

Binary Fission

6.0K
Binary fission is the primary mode of asexual reproduction in prokaryotes, such as bacteria. It results in the production of two genetically identical daughter cells. This highly efficient process ensures the rapid propagation of bacterial populations under favorable conditions and involves coordinated cellular and molecular events.DNA Replication and SeparationThe process begins with the replication of the bacterial chromosome. The circular DNA molecule unwinds at a specific origin of...
6.0K
Coordination of Gene Expression Processes in Bacteria01:29

Coordination of Gene Expression Processes in Bacteria

1.0K
The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
1.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Roles of PknB and CslA in Cell Wall Morphogenesis of Streptomyces.

Molecular microbiology·2026
Same author

Synergistic action of peptidoglycan and teichoic acid synthesis inhibitors leads to cell death by oxidative damage.

Communications biology·2026
Same author

EXPRESSION OF CONJUGATION GENES IS CONTROLLED BY PROCESSIVE ANTITERMINATION AND A NOVEL ZIPPER-TYPE TRANSCRIPTIONAL ATTENUATION MECHANISM.

bioRxiv : the preprint server for biology·2025
Same author

The zinc bound form of the actinomycete derived natural product compound JBIR-141 induces a mitotic phenotype in fission yeast.

Scientific reports·2025
Same author

Antibiotic fosmidomycin protects bacteria from cell wall perturbations by antagonizing oxidative damage-mediated cell lysis.

Frontiers in microbiology·2025
Same author

Biosynthesis of the quinovosamycin nucleoside antibiotics diverges from that of tunicamycins by additional sugar processing genes.

Bioorganic chemistry·2025

相关实验视频

Updated: Apr 13, 2026

Synchronization of Caulobacter Crescentus for Investigation of the Bacterial Cell Cycle
08:02

Synchronization of Caulobacter Crescentus for Investigation of the Bacterial Cell Cycle

Published on: April 8, 2015

12.6K

细胞分裂和染色体分离的协调由Bacillus subtilis中的核状封闭蛋白进行.

Ling Juan Wu1, Jeff Errington

  • 1Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.

Cell
|June 24, 2004
PubMed
概括

核状细胞封闭阻止了细菌细胞在核状细胞附近的分裂. 研究人员确定Noc (YyaA) 是一个关键的抑制剂,对于Bacillus subtilis中正确的细胞分裂部位选择至关重要.

科学领域:

  • 微生物学 微生物学
  • 细胞生物学 细胞生物学
  • 细菌遗传学 细菌遗传学

背景情况:

  • 细菌细胞利用核状闭塞来防止在遗传物质附近的细胞分裂.
  • 众所周知,Min系统在细胞极端调节细胞分裂.

研究的目的:

  • 为了确定Bacillus subtilis中核状细胞封闭的特定效应因子.
  • 了解这种效应因子在细胞分裂部位选择和染色体保护中的作用.

主要方法:

  • 进行了遗传和生理实验.
  • 诺克 (YyaA) 蛋白的功能在 Bacillus subtilis 中进行了研究.
  • 诱导细胞周期扰动以观察细胞分裂模式.

主要成果:

  • 诺克 (YyaA) 被确定为一种非特异性DNA结合蛋白和细胞分裂的抑制剂.
  • Noc 阻止了在核子附近组装的分裂机制.
  • 缺乏Noc和Min系统的细胞由于异常分裂蛋白积累而表现出阻断分裂.

结论:

  • 诺克是Bacillus subtilis.中核细胞封闭机制的关键组成部分.

更多相关视频

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

7.8K
In Vitro Reconstitution of Self-Organizing Protein Patterns on Supported Lipid Bilayers
08:10

In Vitro Reconstitution of Self-Organizing Protein Patterns on Supported Lipid Bilayers

Published on: July 28, 2018

13.0K

相关实验视频

Last Updated: Apr 13, 2026

Synchronization of Caulobacter Crescentus for Investigation of the Bacterial Cell Cycle
08:02

Synchronization of Caulobacter Crescentus for Investigation of the Bacterial Cell Cycle

Published on: April 8, 2015

12.6K
Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast
11:19

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

Published on: February 20, 2017

7.8K
In Vitro Reconstitution of Self-Organizing Protein Patterns on Supported Lipid Bilayers
08:10

In Vitro Reconstitution of Self-Organizing Protein Patterns on Supported Lipid Bilayers

Published on: July 28, 2018

13.0K
  • Noc和Min系统之间的相互作用确保了适当的细胞分裂地点规范.
  • 这些机制可以防止细胞分裂期间染色体破裂.