血压对心理压力的反应性预测了心脏研究中的高血压
Karen A Matthews1, Charles R Katholi, Heather McCreath
1University of Pittsburgh, 3811 O'Hara St, Pittsburgh, PA, USA. matthewska@upmc.edu
Circulation
|June 24, 2004
概括
在年轻人中,在心理压力期间频繁,大血压 (BP) 增加预测未来的高血压. 这一发现强调了压力诱导的高血压反应性作为发展高血压的危险因素.
科学领域:
- 心血管健康 心血管健康
- 心理生理学 心理生理学
- 高血压研究 高血压研究
背景情况:
- 一个长期存在的假设表明,在心理压力期间频繁,大血压 (BP) 增加可能会增加患基本高血压的风险.
- 这项研究调查了心理压力期间的血压变化是否预测了年轻人患高血压的发生率.
研究的目的:
- 为了确定血压对心理压力的反应性是否预测了年轻成年人发生的高血压.
- 检查13年来BP对各种压力任务的反应和高血压的发展之间的关联.
主要方法:
- 用存活分析预测高血压状态在超过4100 normotensive男性和女性 (年龄18-30) 从13年的心脏研究.
- 测量了对三个心理挑战 (冷压器,星球追踪,视频游戏) 的血压反应.
- 高血压被定义为使用抗高血压药物或血压≥140/90毫米升.
主要成果:
- 在对共变量进行调整后,对所有三个心理任务的较高血压反应与较早出现的高血压 (P<0.0001至<0.01) 有显著的关联.
- 对于冷压器任务而言,缩血压反应的效果在女性和白人中显著.
- 在男性中,对视频游戏任务的透静血压反应的影响是显著的.
结论:
- 对心理压力的血压反应显著的年轻人可能会在中年时面临患高血压的风险.
- 压力引起的血压反应是未来高血压的潜在预测因素.
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