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Updated: Jul 22, 2026

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Published on: September 21, 2017

在蛋白质-DNA接口上的适应性:重新设计嵌入的家庭主域以识别非自然的核酸

Matthew D Simon1, Kevan M Shokat

  • 1Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Journal of the American Chemical Society
|July 1, 2004
PubMed
概括

研究人员设计了一个家庭主体蛋白质来识别不自然的DNA核酸. 这种蛋白质-DNA接口适应显示出对修改后的DNA具有很高的亲和力和特异性,类似于自然相互作用.

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