在Rac-依赖细胞迁移中,Drosophila IAP1-介导的卡斯巴酶抑制的作用

Erika R Geisbrecht1, Denise J Montell

  • 1Department of Biological Chemistry, Johns Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.

Cell
|July 10, 2004
PubMed
概括

果虫边界细胞迁移揭示了DIAP1在Rac介导的细胞机动性中具有独立于亡的作用. 通过DIAP1或Dark蛋白抑制Dronc可以挽救RacN17迁移缺陷,突出了DIAP1.1的一个新功能.

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