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Updated: Mar 23, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

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环素A向TRIM5的逆转换解释了猫头对HIV-1的抗性

David M Sayah1, Elena Sokolskaja, Lionel Berthoux

  • 1Department of Microbiology, Columbia University, College of Physicians and Surgeons, 701 West 168th Street, HHSC 1502 New York, New York 10032, USA.

Nature
|July 10, 2004
PubMed
概括

猫头通过TRIMCyp,一种融合蛋白质来限制人类免疫缺陷病毒1型 (HIV-1). 这种抗病毒TRIMCyp基因源于LINE-1逆转移子将环素A (CypA) DNA插入TRIM5基因.

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