走这段距离,或不,与神经质蛋白信号
Louis F Reichardt1, William C Mobley
1Program in Neuroscience, Department of Physiology and Howard Hughes Medical Institute, University of California, San Francisco, 1550 Fourth Street, Room 284A, San Francisco, CA 94143, USA.
Cell
|July 21, 2004
概括
神经生长因子 (NGF) 和神经热素-3 (NT-3) 通过TrkA受体发出信号,但只有NGF促进神经元的存活. 这种差异源于NGF能够触发TrkA受体内化和逆向运输的能力,而不是NT-3.
科学领域:
- 神经科学是一个神经科学.
- 细胞生物学 细胞生物学
- 发育生物学 发展生物学
背景情况:
- 神经生长因子 (NGF) 和神经热素-3 (NT-3) 是关键的神经热素,它们与TrkA受体结合.
- NGF和NT-3都与交感神经元的发育和功能有关.
- 尽管与相同的受体结合,但NGF支持神经元的生存和分化,而NT-3不引起这些相同的结果.
相关概念视频
Cell Migration
16.6K
Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
16.6K
The Synapse
99.9K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
99.9K
Action Potential
10.2K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
10.2K
Action Potential
9.6K
Neurons communicate by firing action potentials—the electrochemical signal that is propagated along the axon. The signal results in the release of neurotransmitters at axon terminals, thereby transmitting information to the nervous system. An action potential is a specific "all-or-none" change in membrane potential that results in a rapid spike in voltage.
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
9.6K
Neurons as Communicators of the Brain
5.2K
Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
Cell Body
The cell body, also known...
5.2K
Neuronal Communication
5.5K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
5.5K


