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在癌细胞中,单细胞分析潜在的蛋白网络

Jonathan M Irish1, Randi Hovland, Peter O Krutzik

  • 1Department of Microbiology & Immunology, Baxter Laboratory of Genetic Pharmacology, Stanford University, Stanford, CA 94305, USA.

Cell
|July 21, 2004
PubMed
概括

癌细胞表现出独特的信号网络概况,通过对蛋白对环境线索反应的单细胞分析揭示出来. 这些概况与遗传学和疾病结果相关,突出显示了癌症的异质性.

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Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...