在社区人口中心力衰竭发生率和存活率的趋势
Véronique L Roger1, Susan A Weston, Margaret M Redfield
1Division of Cardiovascular Diseases and Internal Medicine, Department of Health Sciences Research, Mayo Clinic and Foundation, Rochester, Minn 55095, USA. roger.veronique@mayo.edu
JAMA
|July 22, 2004
概括
心力衰竭发病率保持稳定,但整体生存率有所改善. 然而,女性和老年人生存率的提高不那么明显,这凸显了心力衰竭结果中的性别和年龄差异.
科学领域:
- 心脏病学 心脏病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 心力衰竭 (HF) 疫情需要进一步调查,对社区人口的发病率,存活率和性别特异性趋势的数据有限.
- 了解心力衰竭发病率和存活率的时间趋势对于公共卫生战略和资源配置至关重要.
研究的目的:
- 调查心力衰竭 (HF) 发生率和存活率的时间趋势.
- 为了检查心力衰竭发病率和随着时间的推移生存的性别特异性.
- 测试该假设,即HF发病率下降,生存率有所改善,性别有不同的趋势.
主要方法:
- 基于人口的队列研究利用罗切斯特流行病学项目在明尼苏达州奥姆斯特德县.
- 包括4537名奥姆斯特德县居民在1979年至2000年期间被诊断患有心力衰竭.
- 使用弗雷明翰和临床标准验证心力衰竭诊断.
主要成果:
- 男性 (378/100,000) 的心力衰竭发病率高于女性 (289/100,000),并且随着时间的推移没有变化.
- 在心力衰竭诊断后的整体存活率从1979-1984年 (43%) 到1996-2000年 (52%) 显著改善.
- 与女性和老年人相比,男性和年轻人经历了更大的生存改善.
结论:
- 在这个基于社区的队列中,心力衰竭发病率在20多年内没有下降.
- 心力衰竭诊断后的存活率总体上有所增加,但存在显著的差异.
- 与男性和年轻人群相比,女性和老年人对生存率的改善较小.
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