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Updated: Jul 21, 2026

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice
07:36

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Published on: September 26, 2018

抑制饮食诱导的动脉样硬化和内皮功能障碍在阿波利波蛋白E/血管新生素II型1A受体双淘汰赛小鼠中

Sven Wassmann1, Thomas Czech, Martin van Eickels

  • 1Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.

Circulation
|July 28, 2004
PubMed
概括

抗胰岛素II型1 (AT1) 受体的遗传干扰在小鼠中抑制了动脉样硬化发展. 阻止AT1受体激活可以防止血管氧化应激和内皮功能障碍,这是动脉样硬化的关键因素.

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