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Updated: Jul 8, 2026

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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肺癌中对gefitinib敏感的EGFR突变可以激活抗亡途径

Raffaella Sordella1, Daphne W Bell, Daniel A Haber

  • 1Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center and Harvard Medical School, Building 149, 13th Street, Charlestown, MA 02129, USA.

Science (New York, N.Y.)
|July 31, 2004
PubMed
概括

格菲提尼布向非小细胞肺癌 (NSCLC) 中突变的表皮生长因子受体 (EGFR). 这种药物抑制了生存途径,导致癌细胞死亡,并可能解释其有效性.

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