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Updated: Jul 13, 2026

Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles
07:54

Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles

Published on: November 5, 2020

埃波提隆A在α,β-tubulin上的结合方式通过电子晶体学

James H Nettles1, Huilin Li, Ben Cornett

  • 1Molecular and Systems Pharmacology, Emory University, Atlanta, GA 30322, USA.

Science (New York, N.Y.)
|August 7, 2004
PubMed
概括

确定了与alpha,beta-tubulin结合的epothilone A的结构,揭示了与Taxol.不同的独特结合相互作用. 这一发现澄清了epothilone的含量.

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Microtubule Formation

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