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Updated: Jul 17, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
08:42

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

在骨质疏松症的微的小鼠骨中对素的反应降低

G N Kent1, D G Walker, D V Cohn

  • 1Department of Biocheistry, University of Kansas Medical Center, Kansas City 66103, USA.

Nature
|July 5, 1979
PubMed
概括

No abstract available in PubMed .

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Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...