在成功更换主动脉之后,冠状动脉尺寸的回归
1Department of Internal Medicine, University Hospital, Zurich, Switzerland.
Circulation
|March 1, 1992
概括
大动脉置换后心肌缩的回归降低了冠状动脉大小在患有大动脉疾病的患者. 尽管冠状动脉尺寸减少,但它们仍然足以承受减少的左心室质量.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 血管生物学 血管生物学
背景情况:
- 患有大动脉膜疾病的患者往往会出现心肌缩.
- 减少这种缩对冠状动脉尺寸的影响尚未完全理解.
研究的目的:
- 为了评估心肌缩的回归对冠状动脉尺寸在大动脉置换后的影响.
- 为了评估冠状动脉大小是否仍然相对于手术后的左心室质量相对适当.
主要方法:
- 定量冠状动脉造影用于测量15名患者在大动脉置换前后的主要冠状动脉 (左前下降[LAD],左环[LCx]和右冠状动脉) 的横截面积 (CSA).
- 计算左心室 (LV) 质量,并将冠状动脉大小正常化为每100g的LV质量.
- 作为对照组,有12名健康人群作为对照组.
主要成果:
- 在手术前,与对照组相比,大动脉膜疾病患者的LAD和LCx的CSA显著更大.
- 在门更换后,LAD和LCx的CSA显著下降,但仍然比对照组更大.
- 右冠状动脉的CSA在患者和对照人群之间没有差异,无论是在手术前还是手术后.
- 门更换后LV肌肉质量显著下降,但与对照组相比仍然升高.
- 患者中每100克 LV 质量的 CSA 指数最初异常,但在术后正常化.
结论:
- 大动脉置换导致心肌缩的回归和左主冠状动脉 (LAD和LCx) 的尺寸的减少.
- 尽管减少了,但LAD和LCx的大小仍然足以使手术后的左心室质量正常化.
- 右冠状动脉的大小不受大动脉置换和缩的回归的影响.
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