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Updated: Jul 20, 2026

Peptide Scanning-assisted Identification of a Monoclonal Antibody-recognized Linear B-cell Epitope
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Published on: March 24, 2017

一个鱼单域抗体V区域的晶体结构与酶复合

Robyn L Stanfield1, Helen Dooley, Martin F Flajnik

  • 1Department of Molecular Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|August 21, 2004
PubMed
概括

软骨鱼类拥有独特的新抗原受体 (IgNARs),用于适应性免疫. 它们的单域IgNAR可变区域与传统抗体相似,与高亲和度的抗原结合.

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Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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