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Updated: Jun 28, 2026

DNA Methylation: Bisulphite Modification and Analysis
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DNA Methylation: Bisulphite Modification and Analysis

Published on: October 21, 2011

氧化受损DNA的易发生错误的复制是由高可靠性DNA聚合酶进行的

Gerald W Hsu1, Matthias Ober, Thomas Carell

  • 1Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature
|August 24, 2004
PubMed
概括

呼吸过程中的氧化损伤会造成8-oxoguanine (8oxoG) 的DNA损伤. 这些病变诱使DNA聚合酶错误复制,导致与癌症和衰老相关的突变.

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