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在严重的慢性肺高血压中进行心周适应. 一个手术期间的食管外心回声学研究
1Department of Internal Medicine, University of California, School of Medicine.
Circulation
|April 1, 1992
概括
人体心周适应慢性心脏扩大,在严重的肺高血压中对心脏形状变化的影响最小. 这表明心周是灵活的响应长期的心脏状况.
科学领域:
- 心脏病学 心脏病学
- 生理学 生理学 生理学
背景情况:
- 周心膜限制心脏膨胀,并强调心室的相互依赖性.
- 虽然它限制了急性心脏膨胀,但动物研究表明心脏周围的适应性在慢性疾病中.
- 对于心脏缩和心脏膨胀的人类心周回应仍然未得到充分研究.
研究的目的:
- 为了研究心周在人类心脏缩和扩大中的作用.
- 在患有慢性右心室压力过载的患者中检查心周适应.
主要方法:
- 研究了14名患有由于肺高血压而导致右心室缩和心壮病的患者,他们接受了肺血栓切除术.
- 在心脏切除术前和之后同时进行了手术内转食管多普勒心声学和直接的双心室血动力学测量.
主要成果:
- 皮心切除术后没有观察到任何显著的血液动力学变化,包括心率,肺动脉压力和心脏指数.
- 双管末端透气压力和区域没有显著的变化.
- 多普勒回声心脏学参数和对腹功能的 mitra 输入量保持不变.
结论:
- 心周对慢性严重的右心室压力过载中心脏和隔膜变形的影响最小.
- 证实了人心周围膜随着时间的推移适应心脏大小和几何变化的能力.
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