常规的终止怀孕 - - 我们应该查妊娠形瘤吗?
Michael J Seckl1, Roopinder Gillmore, Marianne Foskett
1Gestational Trophoblastic Disease Unit, Department of Medical Oncology, Charing Cross and Hammersmith Hospitals Campus, Imperial College London, Fulham Palace Road, London W6 8RF, UK. m.seckl@imperial.co.uk
Lancet (London, England)
|August 25, 2004
概括
在妊娠终止后,对妊娠 trofhoblastic 瘤的常规查至关重要. 没有诊断的妇女有更高的严重并发症风险,需要手术干预和化疗.
科学领域:
- 妇科 妇科医生 妇科
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 在非医学性妊娠终止后的受孕产物很少被检查妊娠热瘤 (GTN).
- 未经治疗的GTN可能导致严重的,危及生命的并发症.
研究的目的:
- 评估在进行妊娠终止的妇女中进行妊娠 trofhoblastic瘤查的必要性.
- 为了确定GTN诊断后终止和没有GTN诊断的妇女的结果.
主要方法:
- 追溯的队列研究.
- 在1995年至2001年间,确定了15名没有GTN的妇女和36名患有病理GTN诊断的妇女.
- 随后的并发症率,手术干预和化疗需求的比较.
主要成果:
- 没有GTN诊断的女性经历的危及生命的并发症显著更多 (4/15对0/36;p=0.003).
- 所有没有诊断的妇女都需要手术 (15/15对1/36;p<0.0001).
- 在15名没有诊断的妇女中,有9名需要化疗,而在36名被诊断的妇女中,有2名需要化疗 (p<0.0001).
结论:
- 在妊娠终止后检查妊娠 trofhoblastic 瘤是必不可少的.
- 未能诊断GTN会增加严重孕产妇发病率的风险.
- 应该实施常规病理检查的产品的概念.
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