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Updated: May 5, 2026

Analysis of Cell Cycle Position in Mammalian Cells
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p19ARF直接和差异地控制c-Myc的功能,独立于p53的功能

Ying Qi1, Mark A Gregory, Zhaoliang Li

  • 1Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2175, USA.

Nature
|September 14, 2004
PubMed
概括

瘤抑制剂p19ARF直接抑制瘤转录因子c-Myc,独立于p53. 这种相互作用阻断了c-Myc驱动的细胞增殖和转化,防止瘤形成.

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