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肥胖者的循环单核细胞处于一种促炎状态

Husam Ghanim1, Ahmad Aljada, Deborah Hofmeyer

  • 1Division of Endocrinology, Diabetes, and Metabolism, State University of New York at Buffalo, NY, USA.

Circulation
|September 15, 2004
PubMed
概括

肥胖会触发周围血液单核细胞 (MNC) 的炎症状态,其特征是核因子kappaB (NF-kappaB) 活性增加和炎症基因表达升高. 这种炎症与胰岛素抵抗有关,并由自由脂肪酸 (FFAs) 调节.

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