切断第二阶段的和弦并不能防止急性缺血性 mitra 反
Filiberto Rodriguez1, Frank Langer, Katherine B Harrington
1Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, Calif 94305-5247, USA.
Circulation
|September 15, 2004
概括
切割前额叶片二阶并没有防止羊的急性缺血性额反 (IMR). 这种程序恶化了缩功能,并没有减少IMR严重程度或相关的解剖变化.
科学领域:
- 心血管外科心血管外科
- 心脏机械学 心脏机械学
- 中心门疾病的疾病.
背景情况:
- 缺血性腹反 (IMR) 是心肌梗塞的一个常见并发症.
- 带切割已被提出作为一种手术技术来解决IMR.
- 在预防急性IMR方面切割前额叶片第二阶段的疗效需要进一步研究.
研究的目的:
- 为了评估切割前额叶片第二阶段的切割叶片在预防急性缺血性额回 (IMR) 的有效性.
- 评估这种弦切割在急性缺血期间对左心室 (LV) 缩功能和中枢几何学的影响.
主要方法:
- 六只羊接受了放射性不透明的标记物放置,以获得3D坐标.
- 识别了二级鱼,并用电线陷包围了它们.
- 双飞机视频光学和彩色多普勒透食心电回声学被用于评估腹吐 (MR) 和 LV 功能在急性缺血之前和期间,在弦切割之前和之后.
主要成果:
- 带状切割增加了前侧叶片曲角度,但没有改变有效的叶片长度.
- 通过PRSW评估的左心室缩功能,在带切割后显著下降.
- 急性缺血诱导环状扩张,后面的乳头肌肉位移,以及增加的叶片面积和体积,不论是弦切割.
- 在缺血期间,心肌吐显著增加,而这种增加并未通过二次切割减弱.
结论:
- 切割前额头叶叶片二阶并没有预防或减少急性IMR的严重程度.
- 这项手术导致左心室缩功能受损.
- 弦切割并没有缓解因缺血引起的环状扩张,小册子张面积或小册子张体积.
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