针对急性和威胁关闭的冠状动脉内支架复杂化皮肤透光冠状动脉血管塑造
G S Roubin1, A D Cannon, S K Agrawal
1Division of Cardiovascular Disease, University of Alabama, Birmingham 35294.
Circulation
|March 1, 1992
概括
冠状动脉内支架在血管塑造术后有效地管理了急性和威胁冠状动脉关闭,减少了狭窄并改善了结果. 需要进一步的随机试验来比较支架与其他治疗方法.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
背景情况:
- 急性关闭是皮肤透光冠状动脉血管造形术 (PTCA) 的一个主要限制,导致缺血并发症.
- 冠状动脉内支架被研究为急性和威胁冠状动脉关闭的解决方案.
- 这项研究评估了在这种情况下使用冠状动脉支架的临床和血管学结果.
研究的目的:
- 评估冠状动脉内支架在PTCA后治疗急性冠状动脉关闭和威胁冠状动脉关闭方面的疗效.
- 详细介绍这些疾病治疗用支架治疗的患者的临床和血管学特征.
- 介绍冠状动脉内支架用于急性/威胁关闭的早期临床结果.
主要方法:
- 115名患者 (119个血管) 患有PTCA后急性或威胁性关闭,接受了冠状动脉内支架.
- 病变是使用ACC/AHA标准进行分类的;急性关闭和威胁关闭是根据特定标准定义的,包括TIMI流和剖析.
- 收集了临床和血管学数据,包括住院结果和随访.
主要成果:
- 支架在93%的血管中取得了最佳的血管图像结果,将平均直径狭窄症从83%降低到18%.
- 住院死亡率为1.7%,其中4.2%需要冠状动脉旁路移植 (CABG).
- Q波心肌梗塞 (MI) 发生在7%的患者中,非Q波心肌梗塞发生在9%的患者中;支架血栓发生在7.6%的患者中.
结论:
- 冠状动脉内支架作为气球血管造形术的宝贵补充剂,用于急性或威胁冠状动脉关闭.
- 这些发现支持使用支架来管理复杂的PTCA并发症.
- 随机试验是必要的,以比较支架疗效与替代技术.
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