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Updated: Jul 16, 2026

Direct Observation of Enzymes Replicating DNA Using a Single-molecule DNA Stretching Assay
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Published on: March 23, 2010

通过光激发DNA酶:一个光活性C8 thioether-linked腺素.

Richard Ting1, Leonard Lermer, David M Perrin

  • 1Department of Chemistry, The University of British Columbia, Vancouver, BC, V6T-1Z1, Canada.

Journal of the American Chemical Society
|October 8, 2004
PubMed
概括

研究人员开发了一种新型的光敏感核酸盐,在暴露在光线下重新激活DNA酶活性. 这一发现能够精确控制DNA酶功能,在光药学和生物研究中提供了潜在的应用.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...