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Updated: Jul 15, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
10:14

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography

Published on: May 16, 2014

高度替代的Delta1-pyrrolines的立体选择性合成:与阿兹拉克的异选择性1,3-双极循环添加反应

Satyamaheshwar Peddibhotla1, Jetze J Tepe

  • 1Department of Chemistry, Michigan State University, East Lansing, MI 48823, USA.

Journal of the American Chemical Society
|October 8, 2004
PubMed
概括

这项研究介绍了一种用白银催化的方法,用于从氨基酸衍生的münchnones合成pyrroline支架. 这种反应有效地产生了Delta1-pyrrolines,使用了azlactones和alkenes,没有不必要的副作用.

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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