在缺血性心肌病症的重血管化后,机电绘图识别了功能改善和收缩储备的保留
Habib Samady1, C Joon Choi, Michael Ragosta
1Division of Cardiology, Eastern Virginia Medical School, Sentara Norfolk General Hospital, Norfolk, VA 23505, USA. hsamady@virginia.edu
Circulation
|October 13, 2004
概括
在慢性缺血功能障碍的心脏部分中,近一半的患者在重血管化后表现出收缩性储备,这表明恢复延迟的可能性. 机电绘图可以识别这些细分,以改善患者的治疗结果.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 电子生理学 电子生理学
背景情况:
- 缺血性左心室功能障碍是一个重要的临床问题.
- 重新血管化的目的是恢复血液流动并改善心脏功能.
- 预测功能障碍部分的功能恢复对于指导治疗至关重要.
研究的目的:
- 为了确定缺血性功能障碍细分的比例,以后revascularization收缩储备.
- 评估电机绘图 (EMM) 是否可以识别功能改进或收缩储备的细分.
- 评估收缩储备和功能恢复延迟之间的关系.
主要方法:
- 18名患有严重缺血左心室功能障碍的患者接受了EMM和多布他胺 (D) 心脏磁共振成像 (CMR).
- 患者接受了再血管,随后在4个月和35个月接受了连续D-CMR.
- 在功能恢复方面分析了EMM参数,包括单极电压和EMM比率.
主要成果:
- 在120个功能障碍的部分中,47% (28/60) 显示收缩性储备,而休息功能没有早期改善.
- 与早期休息功能的改善或持续的功能障碍相比,收缩储备的部分表现出明显更大的晚期功能恢复.
- EMM参数,特别是单极电压,在功能障碍的部分较低,与功能状态相关.
结论:
- 功能障碍的心肌段的很大一部分表现出收缩储备和在重血管化后的功能恢复延迟.
- EMM是识别具有功能改善和保留收缩储备的细分的有价值的工具.
- 这些发现对预测缺血性心脏病患者的长期结果有意义.
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